squidpy.gr.spatial_neighbors_radius

squidpy.gr.spatial_neighbors_radius(data, *, radius, spatial_key='spatial', elements_to_coordinate_systems=None, table_key=None, library_key=None, percentile=None, transform=None, set_diag=False, key_added='spatial', copy=False, n_jobs=1)[source]

Create a radius-based graph from spatial coordinates.

Two observations are connected when their Euclidean distance falls within the requested radius. This mode is useful when a physical interaction scale is more meaningful than a fixed number of neighbors.

Parameters:
  • adata – Annotated data object.

  • spatial_key (str) – Key in anndata.AnnData.obsm where spatial coordinates are stored.

  • elements_to_coordinate_systems (dict[str, str] | None) – A dictionary mapping element names of the SpatialData object to coordinate systems. The elements can be either Shapes or Labels. For compatibility, the spatialdata table must annotate all regions keys. Must not be None if adata is a spatialdata.SpatialData.

  • table_key (str | None) – Key in spatialdata.SpatialData.tables where the spatialdata table is stored. Must not be None if adata is a spatialdata.SpatialData.

  • library_key (str | None) – If multiple library_id, column in anndata.AnnData.obs which stores mapping between library_id and obs.

  • radius (float | tuple[float, float]) – Neighborhood radius. If a tuple, the graph is built with the maximum radius and then pruned to the interval [min(radius), max(radius)]. In practice, a single value defines a disk around each observation, whereas a tuple defines an annulus by keeping only edges within the specified distance interval.

  • percentile (float | None) – Percentile of the distances to use as threshold.

  • transform (str | Transform | None) – Adjacency matrix transform ('spectral', 'cosine', or None).

  • set_diag (bool) – Whether to set the diagonal of the connectivities to 1.0.

  • key_added (str) – Key which controls where the results are saved if copy = False.

  • copy (bool) – If True, return the result, otherwise save it to the adata object.

  • n_jobs (int) – Number of parallel jobs used to build the per-library graphs when library_key is set. Each library’s graph is computed independently, so this only has an effect for multi-library data. 1 (default) builds the graphs sequentially and does not change behavior; -1 uses all available CPUs. Has no effect when library_key is None. Speedup is sub-linear (memory-bandwidth bound), and process-based backends pay a one-time worker start-up cost, so parallelism mainly pays off for many large libraries.

Return type:

SpatialNeighborsResult | None

Returns:

If copy = True, returns a SpatialNeighborsResult with the spatial connectivities and distances matrices.

Otherwise, modifies the adata with the following keys:

See also

spatial_neighbors_from_builder

Use RadiusBuilder directly for advanced customization.

squidpy.gr.neighbors.RadiusBuilder

radius-based builder class.